Jean-Pierre Raufman Selected Research

Bethanechol (Duvoid)

2/2018	Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice.
4/2013	Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jean-Pierre Raufman Research Topics

Disease

37	Colonic Neoplasms (Colon Cancer) 01/2022 - 10/2002
28	Neoplasms (Cancer) 01/2022 - 08/2003
7	Carcinogenesis 01/2022 - 11/2011
7	Fibrosis (Cirrhosis) 12/2019 - 06/2010
6	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 10/2005
4	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2011
4	Diarrhea 02/2019 - 11/2016
3	Infections 01/2022 - 04/2005
3	Liver Diseases (Liver Disease) 01/2021 - 07/2005
2	Adenocarcinoma 01/2022 - 04/2013
2	Inflammation (Inflammations) 01/2022 - 01/2016
2	Sclerosing Cholangitis 12/2019 - 02/2018
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 02/2019 - 05/2018
2	Adenoma (Adenomas) 09/2011 - 03/2011
2	Wounds and Injuries (Trauma) 05/2011 - 07/2007
1	Disease Progression 01/2022
1	Hepatocellular Carcinoma (Hepatoma) 01/2022
1	Liver Neoplasms (Liver Cancer) 01/2022
1	Iron Deficiencies 01/2022
1	Cholestasis 01/2020
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 12/2019
1	Acute Liver Failure (Fulminant Hepatic Failure) 12/2018
1	Kidney Diseases (Kidney Disease) 01/2018
1	End Stage Liver Disease 01/2018
1	Sarcopenia 01/2018

Drug/Important Bio-Agent (IBA)

26	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 01/2022 - 10/2002
20	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 10/2002
13	Muscarinic M3 ReceptorIBA 01/2021 - 10/2002
11	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022 - 04/2005
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2009
8	Epidermal Growth Factor (EGF)IBA 01/2017 - 04/2005
7	ErbB Receptors (EGF Receptor)IBA 10/2015 - 10/2003
6	LigandsIBA 03/2019 - 10/2003
6	AzoxymethaneIBA 05/2018 - 05/2008
5	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 04/2005
5	Matrix Metalloproteinases (MMPs)IBA 01/2021 - 04/2009
5	Messenger RNA (mRNA)IBA 03/2019 - 04/2009
4	CateninsIBA 01/2022 - 09/2011
4	Cholinergic Agents (Cholinergics)IBA 03/2019 - 10/2003
4	Taurodeoxycholic AcidIBA 11/2011 - 04/2007
3	p38 Mitogen-Activated Protein KinasesIBA 01/2022 - 01/2017
3	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2022
3	Biological ProductsIBA 12/2021 - 04/2014
3	Biomarkers (Surrogate Marker)IBA 12/2019 - 01/2018
3	Phosphotransferases (Kinase)IBA 03/2019 - 10/2015
3	EnzymesIBA 11/2013 - 04/2007
3	Atropine FDA LinkGeneric 11/2013 - 09/2008
2	CarcinogensIBA 01/2022 - 10/2015
2	MicroRNAs (MicroRNA)IBA 01/2022 - 10/2015
2	Pharmaceutical PreparationsIBA 01/2020 - 04/2005
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 03/2019 - 05/2008
2	Mitogen-Activated Protein KinasesIBA 03/2019 - 01/2017
2	AcidsIBA 02/2019 - 02/2002
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 02/2019 - 05/2018
2	Bethanechol (Duvoid)FDA LinkGeneric 02/2018 - 04/2013
2	Iothalamic Acid (Iotalamic Acid)FDA Link 01/2018 - 01/2018
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2016 - 04/2013
2	Dextran SulfateIBA 10/2015 - 05/2013
2	CollagenIBA 09/2015 - 07/2013
2	Small Interfering RNA (siRNA)IBA 11/2013 - 01/2012
2	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 11/2013 - 09/2008
2	Conditioned Culture MediaIBA 11/2013 - 04/2009
2	Scopolamine (Hyoscine)FDA Link 09/2011 - 06/2010
2	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 04/2009 - 04/2007
2	Matrix Metalloproteinase InhibitorsIBA 04/2009 - 04/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2009 - 05/2008
2	Cholinergic AgonistsIBA 10/2005 - 10/2003
1	AgarIBA 01/2022
1	Erythropoietin FDA Link 01/2022
1	IronIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	Hepatocyte Nuclear Factor 4IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 01/2022
1	Muscarinic M1 ReceptorIBA 01/2022
1	Constitutive Androstane ReceptorIBA 01/2022
1	Rho Guanine Nucleotide Exchange FactorsIBA 01/2021
1	Member 11 Subfamily B ATP Binding Cassette TransporterIBA 01/2020
1	Metformin (Glucophage)FDA LinkGeneric 01/2020
1	Tamoxifen FDA LinkGeneric 01/2020
1	Protein Kinase CIBA 03/2019
1	Protein Kinases (Protein Kinase)IBA 03/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 03/2019
1	Hormones (Hormone)IBA 02/2019
1	23-seleno-25-homotaurocholic acidIBA 02/2019
1	ElementsIBA 01/2019
1	Matrix Metalloproteinase 7 (Matrilysin)IBA 01/2019
1	Collagenases (Collagenase)FDA Link 01/2019
1	Gastrointestinal Hormones (Hormones, Gastrointestinal)IBA 11/2018
1	Dextrans (Dextran)FDA Link 05/2018
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2018
1	3,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA 02/2018
1	S-AdenosylhomocysteineIBA 01/2018
1	Glucuronic Acid (Glucuronate)IBA 01/2018
1	Cystatin CIBA 01/2018
1	Aconitic Acid (Aconitate)IBA 01/2018
1	prostaglandin R2 D-isomerase (prostaglandin D2 synthase)IBA 01/2018

Therapy/Procedure

7	Therapeutics 01/2021 - 07/2005
2	Drug Therapy (Chemotherapy) 01/2018 - 02/2009
1	Immunotherapy 01/2018
1	Transplantation 01/2018